BDBM50282708 CHEMBL289472::Thiophene-2-carboxylic acid benzyl-{2-ethyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-amide

SMILES CCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(Cc1ccccc1)C(=O)c1cccs1

InChI Key InChIKey=KDPHUUTUDFDLBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282708   

TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50282708(CHEMBL289472 | Thiophene-2-carboxylic acid benzyl-...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from AT2 receptor of rat midbrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50282708(CHEMBL289472 | Thiophene-2-carboxylic acid benzyl-...)
Affinity DataIC50:  200nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membraneMore data for this Ligand-Target Pair
In DepthDetails Article