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BDBM50283919 1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-(4-fluoro-phenyl)-piperazine::CHEMBL134964

SMILES: Fc1ccc(cc1)N1CCN(CC1)C1CC[Si](C1)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=OVXHOHJLTMSIKP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50283919   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))
BDBM50283919
PNG
(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-(4-fl...)
Show SMILES Fc1ccc(cc1)N1CCN(CC1)C1CC[Si](C1)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C26H27F3N2Si/c27-20-1-7-23(8-2-20)30-14-16-31(17-15-30)24-13-18-32(19-24,25-9-3-21(28)4-10-25)26-11-5-22(29)6-12-26/h1-12,24H,13-19H2
PDB

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Similars

Article
n/an/a 18n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand


Bioorg Med Chem Lett 4: 415-420 (1994)


Article DOI: 10.1016/0960-894X(94)80007-3
BindingDB Entry DOI: 10.7270/Q2HX1D6M
More data for this
Ligand-Target Pair