BDBM50284283 CHEMBL439489::Endothelin-1 analogue

SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CS)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)c1ccccc1

InChI Key InChIKey=QGIBPTJJDNRVAA-AUCLWABRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284283   

TargetEndothelin-1 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50284283(CHEMBL439489 | Endothelin-1 analogue)
Affinity DataIC50:  8.89E+6nMAssay Description:Concentration required to produce 50% inhibition of binding against ET A receptor obtained from rat thoracic aortic membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50284283(CHEMBL439489 | Endothelin-1 analogue)
Affinity DataIC50:  9.76E+6nMAssay Description:Concentration required to produce 50% inhibition of binding against ET B receptor obtained from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article