BDBM50284661 CHEMBL30086::N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4-oxo-3,4-dihydro-quinazolin-6-yl}-N-pyridin-2-ylmethyl-benzamide

SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccccc2)cc1

InChI Key InChIKey=ACBOMCMCGRRIIN-UHFFFAOYSA-N

Data  3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50284661   

TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50284661(CHEMBL30086 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)
Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-13-6-5-12-30(31)26-16-14-25(15-17-26)22-43-24-38-33-19-18-29(21-32(33)36(43)46)44(23-28-11-7-8-20-37-28)35(45)27-9-3-2-4-10-27/h2-21,24H,22-23H2,1H3
Affinity DataIC50: 6.70nMAssay Description:Binding affinity against AT1 receptor in rabbit aortaMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50284661(CHEMBL30086 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)
Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-13-6-5-12-30(31)26-16-14-25(15-17-26)22-43-24-38-33-19-18-29(21-32(33)36(43)46)44(23-28-11-7-8-20-37-28)35(45)27-9-3-2-4-10-27/h2-21,24H,22-23H2,1H3
Affinity DataIC50: 1.30nMAssay Description:Binding affinity against AT1 receptor in rat adrenal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284661(CHEMBL30086 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)
Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-13-6-5-12-30(31)26-16-14-25(15-17-26)22-43-24-38-33-19-18-29(21-32(33)36(43)46)44(23-28-11-7-8-20-37-28)35(45)27-9-3-2-4-10-27/h2-21,24H,22-23H2,1H3
Affinity DataIC50: 5.10nMAssay Description:Binding affinity against AT1 receptor in human adrenal tissueMore data for this Ligand-Target Pair
In DepthDetails Article