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BDBM50285397 CHEMBL4160788

SMILES: CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](\C=N\OCCO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=SULQOVUHWPGAIV-RDOPTFLASA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285397   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))
BDBM50285397
PNG
(CHEMBL4160788)
Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](\C=N\OCCO)[C@@H](O)[C@H](O)[C@H]2O)cc1
Show InChI InChI=1S/C23H28ClNO7/c1-2-30-17-6-3-14(4-7-17)11-16-12-15(5-8-18(16)24)23-22(29)21(28)20(27)19(32-23)13-25-31-10-9-26/h3-8,12-13,19-23,26-29H,2,9-11H2,1H3/b25-13+/t19-,20-,21+,22-,23+/m1/s1
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Similars

Article
PubMed
n/an/an/an/a 194n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting method


Eur J Med Chem 143: 611-620 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.019
BindingDB Entry DOI: 10.7270/Q2MK6GFZ
More data for this
Ligand-Target Pair