BDBM50285557 (R)-2-[(S)-3-(4-butyl-phenyl)-1-((S)-4-guanidino-1-phenylcarbamoyl-butylcarbamoyl)-propylamino]-propionic acid::CHEMBL249449

SMILES [#6]-[#6]-[#6]-[#6]-c1ccc(-[#6]-[#6]-[#6@H](-[#7]-[#6@H](-[#6])-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-c2ccccc2)cc1

InChI Key InChIKey=FIJLFZRLPPVBHV-YNJKOYDBSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50285557   

Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285557((R)-2-[(S)-3-(4-butyl-phenyl)-1-((S)-4-guanidino-1...)
Affinity DataKi:  2.10nMAssay Description:Inhibitory activity against human gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285557((R)-2-[(S)-3-(4-butyl-phenyl)-1-((S)-4-guanidino-1...)
Affinity DataKi:  36nMAssay Description:Inhibitory activity against human stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285557((R)-2-[(S)-3-(4-butyl-phenyl)-1-((S)-4-guanidino-1...)
Affinity DataKi:  36nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285557((R)-2-[(S)-3-(4-butyl-phenyl)-1-((S)-4-guanidino-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against human collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article