BDBM50286105 CHEMBL318636::Morphinan Cyclic Imine analogue

SMILES CO[C@]12C=C[C@]34C[C@@]1(C)[C@@H](N(C)[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1

InChI Key InChIKey=VAZGOUQKUKGVDX-GRHZWHQTSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50286105   

TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286105(CHEMBL318636 | Morphinan Cyclic Imine analogue)
Affinity DataIC50:  0.360nMAssay Description:Compound was tested for its ability to displace [3H]-DAMGO from mu opioid receptor in hartley guinea pig brain membrane in the presence of 100 nM of ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50286105(CHEMBL318636 | Morphinan Cyclic Imine analogue)
Affinity DataIC50:  9.20nMAssay Description:Compound was tested for its ability to displace [3H]-U-69,593 from Opioid receptor kappa 1 in hartley guinea pig brain membrane in the presence of 10...More data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286105(CHEMBL318636 | Morphinan Cyclic Imine analogue)
Affinity DataIC50:  0.710nMAssay Description:Compound was tested for its ability to displace [3H]-Cl-DPDPE from delta opioid receptor in hartley guinea pig brain membrane in the presence of 100 ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50286105(CHEMBL318636 | Morphinan Cyclic Imine analogue)
Affinity DataIC50:  0.520nMAssay Description:Compound was tested for its ability to displace [3H]-U-69,593 from Opioid receptor kappa 1 in hartley guinea pig brain membrane in the presence of 10...More data for this Ligand-Target Pair
In DepthDetails Article