BDBM50288558 Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-chloro-benzyl ester::CHEMBL101292

SMILES Clc1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1

InChI Key InChIKey=BDQKQZBSECLBLP-UHFFFAOYSA-N

Data  2 IC50

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288558   

TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288558(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-c...)
Show SMILES Clc1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1
Show InChI InChI=1S/C29H20ClNO4/c30-20-12-9-18(10-13-20)16-33-29(32)27(19-11-14-25-26(15-19)35-17-34-25)28-21-5-1-3-7-23(21)31-24-8-4-2-6-22(24)28/h1-15,27H,16-17H2
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288558(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-c...)
Show SMILES Clc1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1
Show InChI InChI=1S/C29H20ClNO4/c30-20-12-9-18(10-13-20)16-33-29(32)27(19-11-14-25-26(15-19)35-17-34-25)28-21-5-1-3-7-23(21)31-24-8-4-2-6-22(24)28/h1-15,27H,16-17H2
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article