BDBM50288878 3-(4-Chloro-phenyl)-2-(4-sulfamoyl-benzoylamino)-propionic acid::CHEMBL152479

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NC(Cc1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=QBCQPXMHHFJBQB-UHFFFAOYSA-N

Data  2 Kd  1 Koff  1 Kon

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50288878   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288878(3-(4-Chloro-phenyl)-2-(4-sulfamoyl-benzoylamino)-p...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NC(Cc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C16H15ClN2O5S/c17-12-5-1-10(2-6-12)9-14(16(21)22)19-15(20)11-3-7-13(8-4-11)25(18,23)24/h1-8,14H,9H2,(H,19,20)(H,21,22)(H2,18,23,24)
Affinity DataKd:  14nMAssay Description:Dissociation constant against human carbonic anhydrase II at 37 degree centigradeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288878(3-(4-Chloro-phenyl)-2-(4-sulfamoyl-benzoylamino)-p...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NC(Cc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C16H15ClN2O5S/c17-12-5-1-10(2-6-12)9-14(16(21)22)19-15(20)11-3-7-13(8-4-11)25(18,23)24/h1-8,14H,9H2,(H,19,20)(H,21,22)(H2,18,23,24)
Affinity DataKoff:  0.0160s-1Assay Description:Kinetic constant for binding human carbonic anhydrase II (Kon=Kd x Koff)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288878(3-(4-Chloro-phenyl)-2-(4-sulfamoyl-benzoylamino)-p...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NC(Cc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C16H15ClN2O5S/c17-12-5-1-10(2-6-12)9-14(16(21)22)19-15(20)11-3-7-13(8-4-11)25(18,23)24/h1-8,14H,9H2,(H,19,20)(H,21,22)(H2,18,23,24)
Affinity DataKon:  0.0220M-1s-1Assay Description:Kinetic constant for binding human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288878(3-(4-Chloro-phenyl)-2-(4-sulfamoyl-benzoylamino)-p...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NC(Cc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C16H15ClN2O5S/c17-12-5-1-10(2-6-12)9-14(16(21)22)19-15(20)11-3-7-13(8-4-11)25(18,23)24/h1-8,14H,9H2,(H,19,20)(H,21,22)(H2,18,23,24)
Affinity DataKd:  15nMAssay Description:Dissociation constant against human carbonic anhydrase II at 37 degree centigradeMore data for this Ligand-Target Pair
In DepthDetails Article