BDBM50290076 CHEMBL558596::N-[(S)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide; hydrochloride

SMILES CN([C@H](CN1CCCC1)c1cccc(NC(C)=O)c1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=FCEBQYDCYXPCAL-JOCHJYFZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50290076   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50290076(CHEMBL558596 | N-[(S)-1-(3-Acetylamino-phenyl)-2-p...)
Affinity DataKi:  0.0855nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50290076(CHEMBL558596 | N-[(S)-1-(3-Acetylamino-phenyl)-2-p...)
Affinity DataKi:  8.40nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290076(CHEMBL558596 | N-[(S)-1-(3-Acetylamino-phenyl)-2-p...)
Affinity DataKi:  14nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]-naltrindole as radiolig...More data for this Ligand-Target Pair
In DepthDetails Article