BDBM50290388 22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-16-ol

SMILES CCO[C@]12Cc3c([nH]c4ccccc34)[C@]3(C)Oc4c5c(CC1N(CC=C)CC[C@@]235)ccc4O

InChI Key InChIKey=DGQGMYGYVZPSDF-OZCDKMRVSA-N

Data  4 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290388   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290388(22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazahept...)
Show SMILES CCO[C@]12Cc3c([nH]c4ccccc34)[C@]3(C)Oc4c5c(CC1N(CC=C)CC[C@@]235)ccc4O
Show InChI InChI=1S/C28H30N2O3/c1-4-13-30-14-12-27-23-17-10-11-21(31)24(23)33-26(27,3)25-19(18-8-6-7-9-20(18)29-25)16-28(27,32-5-2)22(30)15-17/h4,6-11,22,29,31H,1,5,12-16H2,2-3H3/t22?,26-,27-,28+/m0/s1
Affinity DataKi:  11nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290388(22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazahept...)
Show SMILES CCO[C@]12Cc3c([nH]c4ccccc34)[C@]3(C)Oc4c5c(CC1N(CC=C)CC[C@@]235)ccc4O
Show InChI InChI=1S/C28H30N2O3/c1-4-13-30-14-12-27-23-17-10-11-21(31)24(23)33-26(27,3)25-19(18-8-6-7-9-20(18)29-25)16-28(27,32-5-2)22(30)15-17/h4,6-11,22,29,31H,1,5,12-16H2,2-3H3/t22?,26-,27-,28+/m0/s1
Affinity DataKi:  30nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290388(22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazahept...)
Show SMILES CCO[C@]12Cc3c([nH]c4ccccc34)[C@]3(C)Oc4c5c(CC1N(CC=C)CC[C@@]235)ccc4O
Show InChI InChI=1S/C28H30N2O3/c1-4-13-30-14-12-27-23-17-10-11-21(31)24(23)33-26(27,3)25-19(18-8-6-7-9-20(18)29-25)16-28(27,32-5-2)22(30)15-17/h4,6-11,22,29,31H,1,5,12-16H2,2-3H3/t22?,26-,27-,28+/m0/s1
Affinity DataKi:  667nMAssay Description:Compound was evaluated for the binding affinity towards mu opioid receptor in rat brain homogenates using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290388(22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazahept...)
Show SMILES CCO[C@]12Cc3c([nH]c4ccccc34)[C@]3(C)Oc4c5c(CC1N(CC=C)CC[C@@]235)ccc4O
Show InChI InChI=1S/C28H30N2O3/c1-4-13-30-14-12-27-23-17-10-11-21(31)24(23)33-26(27,3)25-19(18-8-6-7-9-20(18)29-25)16-28(27,32-5-2)22(30)15-17/h4,6-11,22,29,31H,1,5,12-16H2,2-3H3/t22?,26-,27-,28+/m0/s1
Affinity DataKi:  765nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor kappa 1 in rat brain homogenates using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article