BDBM50291754 2-Amino-5-ethyl-benzo[d][1,3]oxazin-4-one::CHEMBL146219

SMILES CCc1cccc2nc(N)oc(=O)c12

InChI Key InChIKey=UWDANBPOSJFHEG-UHFFFAOYSA-N

Data  2 KI  1 Koff  1 Kon

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291754   

TargetNeutrophil elastase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50291754(2-Amino-5-ethyl-benzo[d][1,3]oxazin-4-one | CHEMBL...)
Show SMILES CCc1cccc2nc(N)oc(=O)c12
Show InChI InChI=1S/C10H10N2O2/c1-2-6-4-3-5-7-8(6)9(13)14-10(11)12-7/h3-5H,2H2,1H3,(H2,11,12)
Affinity DataKi:  5.01E+3nM Kon:  0.0000776M-1s-1 Koff:  15.1s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50291754(2-Amino-5-ethyl-benzo[d][1,3]oxazin-4-one | CHEMBL...)
Show SMILES CCc1cccc2nc(N)oc(=O)c12
Show InChI InChI=1S/C10H10N2O2/c1-2-6-4-3-5-7-8(6)9(13)14-10(11)12-7/h3-5H,2H2,1H3,(H2,11,12)
Affinity DataKi:  5.10E+3nMAssay Description:Rate of deacylation by human leukocyte elastaseMore data for this Ligand-Target Pair