BDBM50292466 CHEMBL450147::CHEMBL507970::Dimethylgrisabine

SMILES COc1ccc(C[C@@H]2N(C)CCc3cc(OC)c(OC)cc23)cc1Oc1ccc(C[C@H]2N(C)CCc3cc(OC)c(OC)cc23)cc1

InChI Key InChIKey=UHYCXSGUNAWVBW-SAIUNTKASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292466   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50292466(CHEMBL450147 | CHEMBL507970 | Dimethylgrisabine)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50292466(CHEMBL450147 | CHEMBL507970 | Dimethylgrisabine)
Affinity DataIC50:  1.45E+3nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50292466(CHEMBL450147 | CHEMBL507970 | Dimethylgrisabine)
Affinity DataIC50:  5.64E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in Wistar rat striatal membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed