BDBM50292683 (1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate::CHEMBL495555

SMILES CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO

InChI Key InChIKey=OKNJOSGDEWUQIH-RNAHPLFWSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50292683   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed