BDBM50293673 CHEMBL550825::N2-methyl-N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylquinazoline-2,4-diamine

SMILES CN(c1ccccc1)c1nc(Nc2cc(C)n[nH]2)c2ccccc2n1

InChI Key InChIKey=HVHBXBDAWFYVOJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293673   

TargetAurora kinase A(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293673(CHEMBL550825 | N2-methyl-N4-(5-methyl-1H-pyrazol-3...)
Affinity DataKi:  17nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293673(CHEMBL550825 | N2-methyl-N4-(5-methyl-1H-pyrazol-3...)
Affinity DataKi:  312nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293673(CHEMBL550825 | N2-methyl-N4-(5-methyl-1H-pyrazol-3...)
Affinity DataKi:  1.06E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed