BDBM50293844 1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}-1-cyclobutanecarboxylic Acid::CHEMBL560830

SMILES Cc1c(C(=O)c2ccc(Cl)cc2)c2ccc(OC(F)(F)F)cc2n1Cc1cccc(OC2(CCC2)C(O)=O)c1

InChI Key InChIKey=NEIOEHYODVHBBU-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50293844   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293844(1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluorome...)
Affinity DataEC50:  185nMAssay Description:Agonist activity at human PPARalpha receptor expressed in african green monkey COS1 cells cotransfected with fused yeast Gal4-DBD by transactivation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293844(1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluorome...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293844(1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluorome...)
Affinity DataEC50:  12nMAssay Description:Inhibition of human PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293844(1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluorome...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293844(1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluorome...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed