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BDBM50294316 CHEMBL563947::N-(3-(Benzo[d]thiazol-2-yl)thiopen-2-yl)-4-chloro-2-fluorobenzenesulfonamide

SMILES: Fc1cc(Cl)ccc1S(=O)(=O)Nc1sccc1-c1nc2ccccc2s1

InChI Key: InChIKey=KUQTXELKVHRKHG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294316   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Antrax lethal toxin


(Bacillus anthracis)
BDBM50294316
PNG
(CHEMBL563947 | N-(3-(Benzo[d]thiazol-2-yl)thiopen-...)
Show SMILES Fc1cc(Cl)ccc1S(=O)(=O)Nc1sccc1-c1nc2ccccc2s1
Show InChI InChI=1S/C17H10ClFN2O2S3/c18-10-5-6-15(12(19)9-10)26(22,23)21-17-11(7-8-24-17)16-20-13-3-1-2-4-14(13)25-16/h1-9,21H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis lethal factor assessed as cleavage of MAPKK by fluorescence peptide cleavage assay


Bioorg Med Chem 17: 3352-68 (2009)


Article DOI: 10.1016/j.bmc.2009.03.040
BindingDB Entry DOI: 10.7270/Q2D50N0X
More data for this
Ligand-Target Pair