BDBM50297254 3-[2-(3,4-Dihydroxy-phenyl)-3,5-dihydroxy-4-oxo-4H-chromen-7-yloxymethyl]-benzonitrile::CHEMBL551131

SMILES Oc1ccc(cc1O)-c1oc2cc(OCc3cccc(c3)C#N)cc(O)c2c(=O)c1O

InChI Key InChIKey=JBMZSOUKPAAEJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297254   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50297254(3-[2-(3,4-Dihydroxy-phenyl)-3,5-dihydroxy-4-oxo-4H...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of SARS coronavirus helicase assessed as duplex-DNA unwinding by FRET based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50297254(3-[2-(3,4-Dihydroxy-phenyl)-3,5-dihydroxy-4-oxo-4H...)
Affinity DataIC50:  2.54E+4nMAssay Description:Inhibition of ATPase activity of SARS coronavirus helicase assessed as phosphate release by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed