BDBM50297413 CHEMBL560537::N-(3,3-diphenyl-propyl)-nicotinamide::N-(3,3-diphenylpropyl)nicotinamide::N-(3,3-diphenylpropyl)pyridine-3-carboxamide

SMILES O=C(NCCC(c1ccccc1)c1ccccc1)c1cccnc1

InChI Key InChIKey=GDHXZIQAOUBZCC-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50297413   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297413(CHEMBL560537 | N-(3,3-diphenyl-propyl)-nicotinamid...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297413(CHEMBL560537 | N-(3,3-diphenyl-propyl)-nicotinamid...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297413(CHEMBL560537 | N-(3,3-diphenyl-propyl)-nicotinamid...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human soluble EHMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297413(CHEMBL560537 | N-(3,3-diphenyl-propyl)-nicotinamid...)
Affinity DataIC50:  7nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297413(CHEMBL560537 | N-(3,3-diphenyl-propyl)-nicotinamid...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed