BDBM50298036 CHEMBL549725::rac 2-((4-cyano-3-(trifluoromethyl)phenyl)(2,2,2-trifluoroethyl)amino)-N,N-dimethylacetamide

SMILES CC(N(CC(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(=O)N(C)C

InChI Key InChIKey=BEFAEFLFXOZVJY-UHFFFAOYSA-N

Data  5 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50298036   

TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50:  125nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to MR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to ERbeta by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to GR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298036(CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...)
Affinity DataIC50:  1.60E+3nMAssay Description:Binding affinity to AR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed