BDBM50299467 (5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidazol-5-yl)methyl)-32-amino-14,17,20-tribenzyl-5-carbamoyl-23-(carboxymethyl)-8-isobutyl-15-methyl-29-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-2-thia-6,9,12,15,18,21,24,27,30-nonaazatetratriacontan-34-oic acid::CHEMBL583102
SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)CC(O)=O)C(N)=O
InChI Key InChIKey=FWEMQPXASKKIMV-UILVTTEASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50299467
Affinity DataKi: 0.300nMAssay Description:Binding affinity to human NK3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Binding affinity at human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Binding affinity to human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of ([125I]-His3, MePhe7)-NKB from NK3R (unknown origin) transfected in CHO cells by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 0.710nMAssay Description:Agonist activity at wild type human NK3 receptor expressed in HEK293 cells assessed as [3H]IP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0130nMAssay Description:Agonist activity at NK3R (unknown origin) transfected in CHO cells assessed as calcium influx at 10 mMMore data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Agonist activity at human NK3 receptor expressed in cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
Affinity DataEC50: 64nMAssay Description:Agonist activity at human NK3R expressed in CHO cells assessed as induction of Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]His3, MePhe7 from human NK3R expressed in CHO cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Agonist activity at guinea pig NK3 receptor expressed in cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair