BDBM50299618 (S)-N-(3-(isopropylcarbamoyl)phenyl)-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazine-1-carboxamide::CHEMBL572170

SMILES CC(C)NC(=O)c1cccc(NC(=O)N2CCN(C[C@@H]2C)c2ncnc3[nH]cc(C)c23)c1

InChI Key InChIKey=SPKWLNDBVFRGKM-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299618   

TargetLIM domain kinase 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299618((S)-N-(3-(isopropylcarbamoyl)phenyl)-2-methyl-4-(5...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299618((S)-N-(3-(isopropylcarbamoyl)phenyl)-2-methyl-4-(5...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed