BDBM50299701 CHEMBL574602::N6-Methyl-2-phenylethynyl-5'-N-methylcarboxamidoadenosine

SMILES CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)nc(nc12)C#Cc1ccccc1

InChI Key InChIKey=PAFSPMXSTBOTSN-KSVNGYGVSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50299701   

TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299701(CHEMBL574602 | N6-Methyl-2-phenylethynyl-5'-N-meth...)
Affinity DataKi:  0.437nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299701(CHEMBL574602 | N6-Methyl-2-phenylethynyl-5'-N-meth...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299701(CHEMBL574602 | N6-Methyl-2-phenylethynyl-5'-N-meth...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299701(CHEMBL574602 | N6-Methyl-2-phenylethynyl-5'-N-meth...)
Affinity DataKi:  3.28E+4nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299701(CHEMBL574602 | N6-Methyl-2-phenylethynyl-5'-N-meth...)
Affinity DataKi:  4.17E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299701(CHEMBL574602 | N6-Methyl-2-phenylethynyl-5'-N-meth...)
Affinity DataEC50:  151nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed