BDBM50300773 6-(3-(1H-indol-6-yl)benzylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile::CHEMBL584314

SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc4cc[nH]c4c3)nc(nc12)C#N

InChI Key InChIKey=BFJRLYQUSWBFAL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300773   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of California

Curated by ChEMBL
LigandPNGBDBM50300773(6-(3-(1H-indol-6-yl)benzylamino)-9-(3-hydroxypropy...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50300773(6-(3-(1H-indol-6-yl)benzylamino)-9-(3-hydroxypropy...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50300773(6-(3-(1H-indol-6-yl)benzylamino)-9-(3-hydroxypropy...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed