BDBM50300785 9-(3-hydroxypropyl)-6-((2'-(trifluoromethyl)biphenyl-3-yl)methylamino)-9H-purine-2-carbonitrile::CHEMBL571711

SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccccc3C(F)(F)F)nc(nc12)C#N

InChI Key InChIKey=WMURFPFUJHKKKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300785   

TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50300785(9-(3-hydroxypropyl)-6-((2'-(trifluoromethyl)biphen...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50300785(9-(3-hydroxypropyl)-6-((2'-(trifluoromethyl)biphen...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of California

Curated by ChEMBL
LigandPNGBDBM50300785(9-(3-hydroxypropyl)-6-((2'-(trifluoromethyl)biphen...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed