BDBM50301042 CHEMBL572097::N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-(isoquinolin-3-ylamino)-2-methylpropanamide

SMILES C[C@H](NC(=O)C(C)(C)Nc1cc2ccccc2cn1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(c1)C#N

InChI Key InChIKey=ZLUIJMJNGMMQKT-CCLHPLFOSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301042   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301042(CHEMBL572097 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  10.1nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301042(CHEMBL572097 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataEC50:  1.90nMAssay Description:Inverse agonist activity at human CB1 receptor assessed as forskolin-induced cAMP level by adenylyl cyclase activation flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301042(CHEMBL572097 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  117nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed