BDBM50301980 2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluoropyridin-2-yloxy)-4-methylbenzoic acid::CHEMBL572250

SMILES Cc1ccc(C(O)=O)c(Oc2nc(Oc3cccc(c3)-c3cccc(CN)c3)c(F)cc2F)c1

InChI Key InChIKey=HKDXJEFLHNGSRY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301980   

TargetPlasminogen(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301980(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301980(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50:  240nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301980(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed