BDBM50303907 2,3-dihydrobenzo[d]thiazole-2-thiol::CHEMBL570797

SMILES SC1Nc2ccccc2S1

InChI Key InChIKey=PYVUUPVBIDIYPY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303907   

TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303907(2,3-dihydrobenzo[d]thiazole-2-thiol | CHEMBL570797)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303907(2,3-dihydrobenzo[d]thiazole-2-thiol | CHEMBL570797)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Mus musculus)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303907(2,3-dihydrobenzo[d]thiazole-2-thiol | CHEMBL570797)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303907(2,3-dihydrobenzo[d]thiazole-2-thiol | CHEMBL570797)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed