BindingDB logo
myBDB logout

BDBM50304310 CHEMBL596264::trans-3-Oxo-N-(5-phenylisoxazol-3-yl)-3H-spiro[6-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21

InChI Key: InChIKey=IVPSRSHZKXJNAW-VVONHTQRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304310   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50304310
PNG
(CHEMBL596264 | trans-3-Oxo-N-(5-phenylisoxazol-3-y...)
Show SMILES O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21
Show InChI InChI=1S/C22H19N3O4/c26-20(24-19-12-18(29-25-19)14-4-2-1-3-5-14)15-6-9-22(10-7-15)17-13-23-11-8-16(17)21(27)28-22/h1-5,8,11-13,15H,6-7,9-10H2,(H,24,25,26)/t15-,22-
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.10n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human recombinant Y5 receptor


Bioorg Med Chem 17: 6971-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.019
BindingDB Entry DOI: 10.7270/Q2P26Z62
More data for this
Ligand-Target Pair