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BDBM50304362 4-((1-benzoyl-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)diazenyl)-N-(pyrimidin-2-yl)benzenesulfonamide::CHEMBL595581

SMILES: Cc1[nH]n(C(=O)c2ccccc2)c(=O)c1N=Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1

InChI Key: InChIKey=QXBXDIOXPPBSEI-UHFFFAOYSA-N

Data: 1 Kd

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304362   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50304362
PNG
(4-((1-benzoyl-3-methyl-5-oxo-4,5-dihydro-1H-pyrazo...)
Show SMILES Cc1[nH]n(C(=O)c2ccccc2)c(=O)c1N=Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1
Show InChI InChI=1S/C21H17N7O4S/c1-14-18(20(30)28(26-14)19(29)15-6-3-2-4-7-15)25-24-16-8-10-17(11-9-16)33(31,32)27-21-22-12-5-13-23-21/h2-13,26H,1H3,(H,22,23,27)
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Article
PubMed
n/an/an/a 3.66E+3n/an/an/an/an/a



The University of Texas

Curated by ChEMBL


Assay Description
Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopy


Bioorg Med Chem 17: 6983-92 (2009)


Article DOI: 10.1016/j.bmc.2009.08.022
BindingDB Entry DOI: 10.7270/Q2513Z8T
More data for this
Ligand-Target Pair