BDBM50304805 (S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine::CHEMBL609306

SMILES Clc1ccccc1O[C@H]1CCc2ccc(nc12)N1CCNCC1

InChI Key InChIKey=HUUPVTVQRVHGPI-INIZCTEOSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50304805   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304805((S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataKi:  0.700nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assay relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304805((S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptor expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304805((S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataEC50:  87nMAssay Description:Agonist activity against human 5HT2A receptor by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304805((S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataEC50:  300nMAssay Description:Agonist activity against human 5HT2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304805((S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed