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BDBM50304844 4-(2-aminophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one::CHEMBL606695

SMILES: Cn1c(c(-c2ccccc2N)c(=O)n1C)-c1ccc2nccnc2c1

InChI Key: InChIKey=SFGRHGDXSBWQCS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304844   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TGF-beta receptor type I


(Homo sapiens)
BDBM50304844
PNG
(4-(2-aminophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Show SMILES Cn1c(c(-c2ccccc2N)c(=O)n1C)-c1ccc2nccnc2c1
Show InChI InChI=1S/C19H17N5O/c1-23-18(12-7-8-15-16(11-12)22-10-9-21-15)17(19(25)24(23)2)13-5-3-4-6-14(13)20/h3-11H,20H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9.52E+5n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation counting


Bioorg Med Chem Lett 20: 326-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.108
BindingDB Entry DOI: 10.7270/Q2RN37ZK
More data for this
Ligand-Target Pair