BindingDB logo
myBDB logout

BDBM50305219 (+/-)-3-amino-1-(1-(3-hydroxyphenyl)-3,4-dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)propan-1-one::CHEMBL590607

SMILES: NCCC(=O)N1CCc2c([nH]c3ccccc23)C1c1cccc(O)c1

InChI Key: InChIKey=ZGLFKBXFGLFUGJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305219   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50305219
PNG
((+/-)-3-amino-1-(1-(3-hydroxyphenyl)-3,4-dihydro-1...)
Show SMILES NCCC(=O)N1CCc2c([nH]c3ccccc23)C1c1cccc(O)c1
Show InChI InChI=1S/C20H21N3O2/c21-10-8-18(25)23-11-9-16-15-6-1-2-7-17(15)22-19(16)20(23)13-4-3-5-14(24)12-13/h1-7,12,20,22,24H,8-11,21H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 630n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of EG5 after 2 hrs


Bioorg Med Chem Lett 20: 157-60 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.012
BindingDB Entry DOI: 10.7270/Q29G5MXP
More data for this
Ligand-Target Pair