BDBM50308501 CHEMBL603129::Ethyl 5-benzoyl-4-phenylthiazol-2-ylcarbamate::cid_7315331

SMILES CCOC(=O)Nc1nc(c(s1)C(=O)c1ccccc1)-c1ccccc1

InChI Key InChIKey=VMTZCTQCFMWSEO-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50308501   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50308501(CHEMBL603129 | Ethyl 5-benzoyl-4-phenylthiazol-2-y...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50308501(CHEMBL603129 | Ethyl 5-benzoyl-4-phenylthiazol-2-y...)
Affinity DataKi:  206nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50308501(CHEMBL603129 | Ethyl 5-benzoyl-4-phenylthiazol-2-y...)
Affinity DataKi:  391nMAssay Description:Displacement of [3H]PSB-603 from human adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50308501(CHEMBL603129 | Ethyl 5-benzoyl-4-phenylthiazol-2-y...)
Affinity DataKi:  1.64E+3nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 11(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50308501(CHEMBL603129 | Ethyl 5-benzoyl-4-phenylthiazol-2-y...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay