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BDBM50308806 (S)-N-((S)-1-(Hydroxyamino)-5-(3-nitroguanidino)-1-oxopentan-2-yl)-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide::CHEMBL603241

SMILES: NC(NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1)C(=O)NO)=N[N+]([O-])=O

InChI Key: InChIKey=MERBYHIQINGLJP-SRVKXCTJSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308806   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50308806
PNG
((S)-N-((S)-1-(Hydroxyamino)-5-(3-nitroguanidino)-1...)
Show SMILES NC(NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1)C(=O)NO)=N[N+]([O-])=O
Show InChI InChI=1S/C16H28N8O6/c17-16(21-24(29)30)19-8-1-4-10(13(25)22-28)20-14(26)12-6-3-9-23(12)15(27)11-5-2-7-18-11/h10-12,18,28H,1-9H2,(H,20,26)(H,22,25)(H3,17,19,21)/t10-,11-,12-/m0/s1
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antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.61E+6n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of MMP2 by spectrophotometry


Bioorg Med Chem 18: 887-95 (2010)


Article DOI: 10.1016/j.bmc.2009.11.036
BindingDB Entry DOI: 10.7270/Q2J67H1Z
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50308806
PNG
((S)-N-((S)-1-(Hydroxyamino)-5-(3-nitroguanidino)-1...)
Show SMILES NC(NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1)C(=O)NO)=N[N+]([O-])=O
Show InChI InChI=1S/C16H28N8O6/c17-16(21-24(29)30)19-8-1-4-10(13(25)22-28)20-14(26)12-6-3-9-23(12)15(27)11-5-2-7-18-11/h10-12,18,28H,1-9H2,(H,20,26)(H,22,25)(H3,17,19,21)/t10-,11-,12-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.52E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of APN from pig kidney microsomes by spectrophotometry


Bioorg Med Chem 18: 887-95 (2010)


Article DOI: 10.1016/j.bmc.2009.11.036
BindingDB Entry DOI: 10.7270/Q2J67H1Z
More data for this
Ligand-Target Pair