BDBM50309193 4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenol::CHEMBL604459::US10688093, Compound 382_7249_0087::US11701353, Compound 382_7249_0087

SMILES COc1cc(cc(OC)c1OC)-c1cnc(N)c(c1)-c1ccc(O)cc1

InChI Key InChIKey=BZRTYUHZFBKUNX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50309193   

TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50:  209nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50:  288nMAssay Description:The ADP-Glo™ Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50:  209nMAssay Description:The ADP-Glo™ Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50:  288nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent