BDBM50309320 2-(2-(bis(4-fluorophenyl)methyl)-4-(2-methylpyridin-4-yl)thiazol-5-yl)acetic acid::CHEMBL589814

SMILES Cc1cc(ccn1)-c1nc(sc1CC(O)=O)C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=NTDPZJOYVSBVPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309320   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309320(2-(2-(bis(4-fluorophenyl)methyl)-4-(2-methylpyridi...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of[3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309320(2-(2-(bis(4-fluorophenyl)methyl)-4-(2-methylpyridi...)
Affinity DataIC50:  53nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed