BDBM50309344 8-chloro-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7-a]quinazolin-7(1H)-one::CHEMBL590483

SMILES Clc1cccc2N3CCNCCC3NC(=O)c12

InChI Key InChIKey=HWBGCKUNZQBLGD-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50309344   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309344(8-chloro-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309344(8-chloro-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7...)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]LSD from human recombinant 5HT2B receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309344(8-chloro-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7...)
Affinity DataKi:  168nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309344(8-chloro-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7...)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309344(8-chloro-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309344(8-chloro-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed