BDBM50309399 2-(2-(4-chlorobenzyl)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid::CHEMBL603158

SMILES OC(=O)Cc1sc(Cc2ccc(Cl)cc2)nc1-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=FOBMKWHQGXMCSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309399   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309399(2-(2-(4-chlorobenzyl)-4-(4-phenoxyphenyl)thiazol-5...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of[3H]PGD2 from human CRTH2 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309399(2-(2-(4-chlorobenzyl)-4-(4-phenoxyphenyl)thiazol-5...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309399(2-(2-(4-chlorobenzyl)-4-(4-phenoxyphenyl)thiazol-5...)
Affinity DataIC50:  66nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed