BDBM50309888 4-(6-Chloro-5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo-[3.2.2]nonane::CHEMBL603052
SMILES Cc1nc2nc(oc2cc1Cl)N1CCN2CCC1CC2
InChI Key InChIKey=PKPRDSSAMMLSLJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50309888
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 3.19nMAssay Description:Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
Affinity DataKi: 244nMAssay Description:Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 244nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Agonist activity at human 5HT3 receptor expressed in human skin epithelial cells assessed as stimulation of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of 5HT3 receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Agonist activity at alpha7 nAChRMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair