BDBM50310152 CHEMBL597277::rac-2-amino-4-(2,6-diethylpyridin-4-yl)-1-methyl-4-(3-(pyrimidin-5-yl)phenyl)-1H-imidazol-5(4H)-one

SMILES CCc1cc(cc(CC)n1)C1(N=C(N)N(C)C1=O)c1cccc(c1)-c1cncnc1

InChI Key InChIKey=QQPRKWVAAAEILV-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50310152   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310152(CHEMBL597277 | rac-2-amino-4-(2,6-diethylpyridin-4...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310152(CHEMBL597277 | rac-2-amino-4-(2,6-diethylpyridin-4...)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310152(CHEMBL597277 | rac-2-amino-4-(2,6-diethylpyridin-4...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair