BDBM50313121 3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3-yl)-1H-indole::CHEMBL1086719

SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1

InChI Key InChIKey=INCWGVPGPVQEOT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313121   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313121(3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313121(3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed