BDBM50313524 3,5-dioxo-4-(3-(piperidin-1-yl)propyl)-2-(3-(trifluoromethyl)phenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile::3,5-dioxo-4-(3-piperidin-1-ylpropyl)-2-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile::CHEMBL1084114

SMILES FC(F)(F)c1cccc(c1)-n1nc(C#N)c(=O)n(CCCN2CCCCC2)c1=O

InChI Key InChIKey=HKAVWQNLXOMWLR-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50313524   

TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313524(3,5-dioxo-4-(3-(piperidin-1-yl)propyl)-2-(3-(trifl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313524(3,5-dioxo-4-(3-(piperidin-1-yl)propyl)-2-(3-(trifl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313524(3,5-dioxo-4-(3-(piperidin-1-yl)propyl)-2-(3-(trifl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313524(3,5-dioxo-4-(3-(piperidin-1-yl)propyl)-2-(3-(trifl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed