BDBM50314929 6-(3,5-dimethylisoxazol-4-yl)-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one::CHEMBL1089877

SMILES Cc1noc(C)c1-c1ccc2OC3(CCN(CC3)C(=O)c3cc(C)c4[nH]ncc4c3)CC(=O)c2c1

InChI Key InChIKey=NGINKMCRRVENRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314929   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314929(6-(3,5-dimethylisoxazol-4-yl)-1'-(7-methyl-1H-inda...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314929(6-(3,5-dimethylisoxazol-4-yl)-1'-(7-methyl-1H-inda...)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed