BDBM50317449 7-benzyl-5-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine::CHEMBL1095424

SMILES Nc1n[nH]c2nc(N3CCCC3)c3CN(Cc4ccccc4)CCc3c12

InChI Key InChIKey=LDIBYHVHPKHRLT-UHFFFAOYSA-N

Data  2 EC50

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317449   

TargetBombesin receptor subtype-3(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50317449(7-benzyl-5-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-3H...)
Show SMILES Nc1n[nH]c2nc(N3CCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C20H24N6/c21-18-17-15-8-11-25(12-14-6-2-1-3-7-14)13-16(15)20(22-19(17)24-23-18)26-9-4-5-10-26/h1-3,6-7H,4-5,8-13H2,(H3,21,22,23,24)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assayMore data for this Ligand-Target Pair
TargetBombesin receptor subtype-3(RAT)
AMRI

Curated by ChEMBL
LigandPNGBDBM50317449(7-benzyl-5-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-3H...)
Show SMILES Nc1n[nH]c2nc(N3CCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C20H24N6/c21-18-17-15-8-11-25(12-14-6-2-1-3-7-14)13-16(15)20(22-19(17)24-23-18)26-9-4-5-10-26/h1-3,6-7H,4-5,8-13H2,(H3,21,22,23,24)
Affinity DataEC50:  965nMAssay Description:Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assayMore data for this Ligand-Target Pair