BDBM50317736 3-benzyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098402

SMILES CS(=O)(=O)c1ccc(cc1)-c1cccc(c1)-c1c(Cc2ccccc2)cnc2c(cccc12)C(F)(F)F

InChI Key InChIKey=NTXMYMGYFCGBAL-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317736   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317736(3-benzyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(t...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in HuH7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317736(3-benzyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(t...)
Affinity DataIC50:  372nMAssay Description:Displacement of [3H]T0901317 from LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317736(3-benzyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(t...)
Affinity DataIC50:  109nMAssay Description:Displacement of [3H]T0901317 from LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed