BDBM50317747 4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1097140

SMILES CS(=O)(=O)c1cc(c(F)cc1F)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F

InChI Key InChIKey=UWFHFVAFWATDDO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317747   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317747(4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [3H]T0901317 from LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317747(4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]T0901317 from LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317747(4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl...)
Affinity DataEC50:  565nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in HuH7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed