BDBM50317930 (2R*,3S*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-3,4-diphenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1098066

SMILES O[C@@]1(C[C@@H](CSC#N)O[C@H]([C@@H]1c1ccccc1)c1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=LKLSPOXUXUIYBW-QORCZRPOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317930   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50317930((2R*,3S*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-3,4...)
Affinity DataIC50:  2.89E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50317930((2R*,3S*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-3,4...)
Affinity DataIC50:  1.11nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed