BDBM50319620 CHEMBL1084715::N-(4-(4-(2-(Ethylamino)-4-methylthiazol-5-yl)pyrimidin-2-ylamino)benzyl)acetamide

SMILES CCNc1nc(C)c(s1)-c1ccnc(Nc2ccc(CNC(C)=O)cc2)n1

InChI Key InChIKey=VEJCMMPVTMQFME-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50319620   

TargetAurora kinase B(Homo sapiens (Human))
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(CHEMBL1084715 | N-(4-(4-(2-(Ethylamino)-4-methylth...)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(CHEMBL1084715 | N-(4-(4-(2-(Ethylamino)-4-methylth...)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(CHEMBL1084715 | N-(4-(4-(2-(Ethylamino)-4-methylth...)
Affinity DataKi:  9nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(CHEMBL1084715 | N-(4-(4-(2-(Ethylamino)-4-methylth...)
Affinity DataKi:  32nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(CHEMBL1084715 | N-(4-(4-(2-(Ethylamino)-4-methylth...)
Affinity DataKi:  38nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(CHEMBL1084715 | N-(4-(4-(2-(Ethylamino)-4-methylth...)
Affinity DataKi:  171nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(CHEMBL1084715 | N-(4-(4-(2-(Ethylamino)-4-methylth...)
Affinity DataKi:  240nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed