BDBM50319955 (1S,4S)-2-(5-(benzo[b]thiophen-5-yl)pyrimidin-2-yl)-5-methyl-2,5-diazabicyclo[2.2.1]heptane::CHEMBL1085806

SMILES CN1C[C@@H]2C[C@H]1CN2c1ncc(cn1)-c1ccc2sccc2c1

InChI Key InChIKey=GONGSLGOCPNPSS-HOTGVXAUSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50319955   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319955((1S,4S)-2-(5-(benzo[b]thiophen-5-yl)pyrimidin-2-yl...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319955((1S,4S)-2-(5-(benzo[b]thiophen-5-yl)pyrimidin-2-yl...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319955((1S,4S)-2-(5-(benzo[b]thiophen-5-yl)pyrimidin-2-yl...)
Affinity DataEC50:  3.30E+4nMAssay Description:Agonist activity at human alpha7 nACHR expressed in Xenopus oocyte assessed as activation of current by voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed